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  • Influence of heparin and a low molecular weight heparinoid on specific endogenous and exogenous fibrinolytic factors during rest and exercise.

    de Boer A, Kluft C, Dooijewaard G, Kasper FJ, Kroon JM, Breimer DD, Stiekema JC, Cohen AF

    Thrombosis and haemostasis, 1992 Nov; 68(5):550-5

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  • Highly variable anticoagulant response after subcutaneous administration of high-dose (12,500 IU) heparin in patients with myocardial infarction and healthy volunteers.

    Kroon C, ten Hove WR, de Boer A, Kroon JM, van der Pol JM, Harthoorn-Lasthuizen EJ, Schoemaker HC, van der Meer FJ, Cohen AF

    Circulation, 1992 Oct; 86(5):1370-5

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  • Diurnal rhythm in anticoagulant effect of heparin during a low dose constant rate infusion. A study in healthy volunteers.

    Krulder JW, de Boer A, van den Besselaar AM, Cohen AF, Schoemaker HC, Briët E, Meinders AE

    Thrombosis and haemostasis, 1992 Jul; 68(1):30-2

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  • Pronounced effects of the combination of a new thromboxane antagonist (GR32191) and heparin on bleeding time in man.

    de Boer A, Kroon JM, Kroon C, van Vliet A, Schoemaker HC, Breimer DD, Donoghue S, Cohen AF

    Thrombosis and haemostasis, 1992 Jul; 68(1):24-9

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  • Long-term effects of tolrestat on symptomatic diabetic sensory polyneuropathy.

    van Gerven JM, Lemkes HH, van Dijk JG

    Journal of diabetes and its complications, 1992 Apr; 6(1):45-8

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  • Intraindividual variability in nifedipine pharmacokinetics and effects in healthy subjects.

    Soons PA, Schoemaker HC, Cohen AF, Breimer DD

    Journal of clinical pharmacology, 1992 Mar; 32(4):324-31

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  • Assessment of hepatic blood flow in healthy subjects by continuous infusion of indocyanine green.

    Soons PA, De Boer A, Cohen AF, Breimer DD

    British journal of clinical pharmacology, 1991 Nov; 32(6):697-704

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  • Influence of gastric acidity on the bioavailability of digoxin.

    Cohen AF, Kroon R, Schoemaker R, Hoogkamer H, van Vliet A

    Annals of internal medicine, 1991 Sep; 115(7):540-5

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  • Cardiovascular effects of a novel enkephalin analogue, 443C81, in humans.

    Cohen AF, Harkin N, Posner J

    Journal of cardiovascular pharmacology, 1990 Sep; 16(3):455-60

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Browse 1015 publications in the CHDR library

  • Clinical studies & Development
  • CHDR's story
  • People
  • Education
  • Library

Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
    • Psychiatry
    • Sleep disorders

    Immunology & Inflammation

    • Immuno-inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- and microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessments
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac and endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Biomarker Laboratory
    • Cardiology Services
    • Pharmacokinetics and pharmacometrics
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 1015 publications in the CHDR library

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