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Browse our Cardiac & endovascular function assessments publications

The CHDR library contains a wealth of research and innovative publications that pushes our quality of work towards the highest standards.
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  • The pharmacokinetics and effects of a long-acting preparation of superoxide dismutase (PC-SOD) in man.

    Broeyer FJ, van Aken BE, Suzuki J, Kemme MJ, Schoemaker HC, Cohen AF, Mizushima Y, Burggraaf J

    British journal of clinical pharmacology, 2007 Dec; 65(1):22-9

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  • Local tissue factor pathway inhibitor release in the human forearm.

    Kemme MJ, Burggraaf J, Schoemaker RC, Cohen AF, Kluft C, Chia S, Webb DJ, Newby DE

    Thrombosis and haemostasis, 2003 Feb; 89(3):438-45

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  • Endothelial binding of recombinant tissue plasminogen activator: quantification in vivo using a recirculatory model.

    Kemme MJ, Schoemaker RC, Burggraaf J, van der Linden M, Noordzij M, Moerland M, Kluft C, Cohen AF

    Journal of pharmacokinetics and pharmacodynamics, 2003 Jan; 30(1):3-22

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  • Quantification of heparin-induced TFPI release: a maximum release at low heparin dose.

    Kemme MJ, Burggraaf J, Schoemaker RC, Kluft C, Cohen AF

    British journal of clinical pharmacology, 2002 Dec; 54(6):627-34

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  • Sorbitol as a marker for drug-induced decreases of variable duration in liver blood flow in healthy volunteers.

    Burggraaf J, Schoemaker RC, Lentjes EG, Cohen AF

    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2000 Nov; 12(2):133-9

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  • Effects of changing liver blood flow by exercise and food on kinetics and dynamics of saruplase.

    van Griensven JM, Burggraaf KJ, Gerloff J, Günzler WA, Beier H, Kroon R, Huisman LG, Schoemaker RC, Kluft K, Cohen AF

    Clinical pharmacology and therapeutics, 1995 Apr; 57(4):381-9

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  • Hypoxia-induced arterial endothelin does not influence peripheral vascular tone.

    Blauw GJ, Westendorp RG, Srivastava N, Burggraaf K, Frölich M, Simons R, Cohen AF, Meinders AE

    Journal of cardiovascular pharmacology, 1995 Mar

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  • The pharmacokinetic and pharmacodynamic interactions of ramipril with propranolol.

    van Griensven JM, Seibert-Grafe M, Schoemaker HC, Frölich M, Cohen AF

    European journal of clinical pharmacology, 1993 Apr; 45(3):255-60

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  • Comparative effects of felodipine, nitrendipine and nifedipine in healthy subjects: concentration-effect relationships of racemic drugs and enantiomers.

    Soons PA, Cohen AF, Breimer DD

    European journal of clinical pharmacology, 1993 Apr; 44(2):113-20

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Browse 1016 publications in the CHDR library

  • Clinical studies & Development
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Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
    • Psychiatry
    • Sleep disorders

    Immunology & Inflammation

    • Immuno-inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- and microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessments
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac and endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Biomarker Laboratory
    • Cardiology Services
    • Pharmacokinetics and pharmacometrics
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 1016 publications in the CHDR library

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