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The CHDR library contains a wealth of research and innovative publications that pushes our quality of work towards the highest standards.
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  • Pharmacokinetics of saruplase, a recombinant unglycosylated human single-chain urokinase-type plasminogen activator and its effects on fibrinolytic and haemostatic parameters in healthy male subjects.

    de Boer A, Kluft C, Gerloff J, Dooijewaard G, Günzler WA, Beier H, van der Meer FJ, Cohen AF

    Thrombosis and haemostasis, 1993 Aug; 70(2):320-5

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  • A comparison of the concentration-effect relationships of midazolam for EEG-derived parameters and saccadic peak velocity.

    Van Steveninck AL, Mandema JW, Tuk B, Van Dijk JG, Schoemaker HC, Danhof M, Cohen AF

    British journal of clinical pharmacology, 1993 Jul; 36(2):109-15

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  • Interaction study between nifedipine and recombinant tissue-type plasminogen activator in healthy subjects.

    De Boer A, Kluft C, Kasper FJ, Kroon JM, Schoemaker HC, Breimer DD, Soons PA, Cohen AF

    British journal of clinical pharmacology, 1993 Jul; 36(2):99-104

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  • A cross-over comparison of the anti-clotting effects of three low molecular weight heparins and glycosaminoglycuronan.

    Stiekema JC, Van Griensven JM, Van Dinther TG, Cohen AF

    British journal of clinical pharmacology, 1993 Jun; 36(1):51-6

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  • Cimetidine does not influence the metabolism of the H1-receptor antagonist ebastine to its active metabolite carebastine.

    Van Rooij J, Schoemaker HC, Bruno R, Reinhoudt JF, Breimer DD, Cohen AF

    British journal of clinical pharmacology, 1993 May; 35(6):661-3

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  • Good clinical practice: a question of balance.

    Wallnöfer AE, Cohen AF

    British journal of clinical pharmacology, 1993 Apr; 35(5):449-50

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  • Pharmacodynamic interactions of diazepam and intravenous alcohol at pseudo steady state.

    van Steveninck AL, Gieschke R, Schoemaker HC, Pieters MS, Kroon JM, Breimer DD, Cohen AF

    Psychopharmacology, 1993 Apr; 110(4):471-8

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  • Carbamazepine and lamotrigine in healthy volunteers: relevance to early tolerance and clinical trial dosage.

    Hamilton MJ, Cohen AF, Yuen AW, Harkin N, Land G, Weatherley BC, Peck AW

    Epilepsia, 1993 Apr; 34(1):166-73

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  • The pharmacokinetic and pharmacodynamic interactions of ramipril with propranolol.

    van Griensven JM, Seibert-Grafe M, Schoemaker HC, Frölich M, Cohen AF

    European journal of clinical pharmacology, 1993 Apr; 45(3):255-60

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Browse 1016 publications in the CHDR library

  • Clinical studies & Development
  • CHDR's story
  • People
  • Education
  • Library

Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
    • Psychiatry
    • Sleep disorders

    Immunology & Inflammation

    • Immuno-inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- and microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessments
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac and endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Biomarker Laboratory
    • Cardiology Services
    • Pharmacokinetics and pharmacometrics
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 1016 publications in the CHDR library

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