Key publication
893
Therapeutic Areas
Methods & challenges

Key publication

Pharmacokinetics of oral fumarates in healthy subjects.

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Ovariectomy and 17beta-estradiol modulate disease progression of a mouse model of ALS.

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Pharmacokinetics of rectal tramadol in postoperative paediatric patients.

Key publication

Glucose homeostasis in abdominal obesity: hepatic hyperresponsiveness to growth hormone action.

1 July 2004

American journal of physiology. Endocrinology and metabolism

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Key publication

Pharmacokinetic/pharmacodynamic assessment of tolerance to central nervous system effects of a 3 mg sustained release tablet of rilmenidine in hypertensive patients.

Key publication

Effects of a nonpeptide motilin receptor antagonist on proximal gastric motor function.

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Gallbladder volume as a biomarker for the motilin effect in healthy volunteers and patients with functional dyspepsia.

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The application of the principles of clinical drug development to pharmacological challenge tests of the serotonergic system.

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No evidence of the usefulness of eye blinking as a marker for central dopaminergic activity.