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The CHDR library contains a wealth of research and innovative publications that pushes our quality of work towards the highest standards.
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  • Immunomonitoring of Tacrolimus in Healthy Volunteers: The First Step from PK- to PD-Based Therapeutic Drug Monitoring?

    In 't Veld AE, Grievink HW, Saghari M, Stuurman FE, de Kam ML, de Vries APJ, de Winter BCM, Burggraaf J, Cohen AF, Moerland M

    International journal of molecular sciences, 2019 Sep

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  • The selective orexin-2 antagonist seltorexant (JNJ-42847922/MIN-202) shows antidepressant and sleep-promoting effects in patients with major depressive disorder

    Kasper Recourt, Peter de Boer, Rob Zuiker, Remy Luthringer, Justine Kent, Peter van der Ark, Ilse Van Hove, Joop van Gerven, Gabriel Jacobs, Luc van Nueten and Wayne Drevets

    2019 Sep

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  • The selective orexin-2 antagonist seltorexant (JNJ-42847922/MIN-202) shows antidepressant and sleep-promoting effects in patients with major depressive disorder.

    Recourt K, de Boer P, Zuiker R, Luthringer R, Kent J, van der Ark P, Van Hove I, van Gerven J, Jacobs G, van Nueten L, Drevets W

    Translational psychiatry, 2019 Sep; 9(1):216

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  • Rare disease specialists and clinical pharmacologists unite: Increase collection of longitudinal data!

    Santen GWE, Cohen AF

    British journal of clinical pharmacology, 2019 Sep

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  • The Oral Pheneticillin Absorption Test: An Accurate Method to Identify Patients with Inadequate Oral Pheneticillin Absorption

    Anneke C. Dijkmans, Dinemarie M. Kweekel, Jaap T. van Dissel, Michiel J. van Esdonk , Ingrid M. C. Kamerling and Jacobus Burggraaf

    Antibiotics , 2019 Sep

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  • An observational study on survival rates of patients with out-of-hospital cardiac arrest in the Netherlands after improving the ‘chain of survival’

    Matthijs de Visser, Jan Bosch, Marianne Bootsma, Suzanne Cannegieter, Annemarie van Dijk, Christian Heringhaus, Jan de Nooij, Nienke Terpstra, Nicolas Peschanski, Koos Burggraaf

    BMJ Open, 2019 Sep

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  • Gepersonaliseerde omalizumabbehandeling bij patiënten met chronische spontane urticaria – een praktische handleiding

    T. Niemeyer-van der Kolk, M.S. van Maaren, dr. M.B.A. van Doorn

    NED TIJDSCHR ALLERGIE, ASTMA, KLIN IMMUNOL , 2019 Sep

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  • The simplified oral flucloxacillin absorption test: an accurate method to identify patients with inadequate oral flucloxacillin absorption.

    Dijkmans AC, Kweekel DM, Balmforth C, van Esdonk MJ, van Dissel JT, Burggraaf J, Kamerling IMC

    The Netherlands journal of medicine, 2019 Sep; 77(7):255-260

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  • DNL104, a centrally penetrant RIPK1 inhibitor, inhibits RIP1 kinase phosphorylation in a randomized phase I ascending dose study in healthy volunteers.

    Grievink HW, Heuberger JAAC, Huang F, Chaudhary R, Birkhoff WAJ, Tonn GR, Mosesova S, Erickson R, Moerland M, Haddick PCG, Scearce-Levie K, Ho C, Groeneveld GJ

    Clinical pharmacology and therapeutics, 2019 Aug

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Browse 853 publications in the CHDR library

  • Clinical studies & Development
  • CHDR's story
  • People
  • Education
  • Library

Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
    • Psychiatry
    • Sleep disorders

    Immunology & Inflammation

    • Immuno-Inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- & microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessements
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac & Endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Pharmacokinetics and pharmacometrics
    • CHDR Cardiology
    • Biomarker Laboratory
    • Data Management
    CHDR InnoS
    Participate in a Clinical Trial proefpersoon.nl

Browse 853 publications in the CHDR library

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