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Under-representation of elderly in clinical trials: An analysis of the initial approval documents in the Food and Drug Administration database.

Ruiter R, Burggraaf J, Rissmann R

British journal of clinical pharmacology, 2019 Jan

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The effect of repeated methotrexate injections on the quality of life of children with rheumatic diseases.

Jacobse J, Ten Voorde W, Rissmann R, Burggraaf J, Ten Cate R, Schrier L

European journal of pediatrics, 2019 Jan; 178(1):17-20

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The oral splicing modifier RG7800 increases full length survival of motor neuron 2 mRNA and survival of motor neuron protein: Results from trials in healthy adults and patients with spinal muscular atrophy.

Kletzl H, Marquet A, Günther A, Tang W, Heuberger J, Groeneveld GJ, Birkhoff W, Mercuri E, Lochmüller H, Wood C, Fischer D, Gerlach I, Heinig K, Bugawan T, Dziadek S, Kinch R, Czech C, Khwaja O

Neuromuscular disorders : NMD, 2019 Jan; 29(1):21-29

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Population pharmacokinetic modelling of intravenous paracetamol in fit older people displays extensive unexplained variability.

Mian P, van Esdonk MJ, Olkkola KT, de Winter BCM, Liukas A, Spriet I, Tibboel D, Petrovic M, Koch BCP, Allegaert K

British journal of clinical pharmacology, 2019 Jan; 85(1):126-135

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The ultraviolet B inflammation model: postinflammatory hyperpigmentation and validation of a reduced UVB exposure paradigm for inducing hyperalgesia in healthy subjects.

Siebenga PS, van Amerongen G, Klaassen ES, de Kam ML, Rissmann R, Groeneveld GJ

European journal of pain (London, England), 2018 Dec

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Predictors of simulated driving performance in Huntington's disease.

Jacobs M, Hart EP, Mejia Miranda Y, Groeneveld GJ, van Gerven JMA, Roos RAC

Parkinsonism & related disorders, 2018 Dec

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Failure to Respond after Reinstatement of Antidepressant Medication: A Systematic Review.

Bosman RC, Waumans RC, Jacobs GE, Oude Voshaar RC, Muntingh ADT, Batelaan NM, van Balkom AJLM

Psychotherapy and psychosomatics, 2018 Dec; 87(5):268-275

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New approaches in psychiatric drug development.

van der Doef TF, Zaragoza Domingo S, Jacobs GE, Drevets WC, Marston HM, Nathan PJ, Tome MB, Tamminga CA, van Gerven JMA, Kas MJH

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2018 Dec; 28(9):983-993

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A randomized Phase 2 study to evaluate the orexin-2 receptor antagonist seltorexant in individuals with insomnia without psychiatric comorbidity.

De Boer P, Drevets WC, Rofael H, van der Ark P, Kent JM, Kezic I, Parapatics S, Dorffner G, van Gerven J, Beneš H, Keicher C, Jahn H, Seiden DJ, Luthringer R

Journal of psychopharmacology (Oxford, England), 2018 Dec; 32(6):668-677

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