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Accelerating vaccine trial conduct in a pandemic with a hot spot-based inclusion strategy using trial and epidemic simulation.

van der Plas JL, van Esdonk MJ, Kamerling IMC, Cohen AF

Clinical and translational science, 2021 Jul

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Neoadjuvant Treatment with Angiogenesis-Inhibitor Dovitinib Prior to Local Therapy in Hepatocellular Carcinoma: A Phase II Study.

Woei-A-Jin FJSH, Weijl NI, Burgmans MC, Fariña Sarasqueta A, van Wezel JT, Wasser MNJM, Coenraad MJ, Burggraaf J, Osanto S

The oncologist, 2021 Jul

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Commentary on "Investigator brochures for phase I/II trials lack information on the robustness of preclinical safety studies" by Sievers et al.

Rissmann R, Zuiker R

British journal of clinical pharmacology, 2021 Jul; 87(7):2633-2634

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The impact of lockdown on pediatric ED visits and hospital admissions during the COVID19 pandemic: a multicenter analysis and review of the literature.

Kruizinga MD, Peeters D, van Veen M, van Houten M, Wieringa J, Noordzij JG, Bekhof J, Tramper-Stranders G, Vet NJ, Driessen GJA

European journal of pediatrics, 2021 Jul; 180(7):2271-2279

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Pharmacological Interactions between the Dual Orexin Receptor Antagonist Daridorexant and Ethanol in a Double-Blind, Randomized, Placebo-Controlled, Double-Dummy, Four-Way Crossover Phase I Study in Healthy Subjects.

Berger B, Brooks S, Zuiker R, Richard M, Muehlan C, Dingemanse J

CNS drugs, 2021 Jun; 34(12):1253-1266

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The impact of the global COVID-19 pandemic on the conduct of clinical trials: Return to normalcy by considering the practical impact of a structured ethical analysis.

Vissers MFJM, Cohen AF, Van Gerven JMA, Groeneveld GJ

British journal of clinical pharmacology, 2021 Jun; 87(3):837-844

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First Clinical Study with AP30663 - a K 2 Channel Inhibitor in Development for Conversion of Atrial Fibrillation.

Gal P, Klaassen ES, Bergmann KR, Saghari M, Burggraaf J, Kemme MJB, Sylvest C, Sørensen U, Bentzen BH, Grunnet M, Diness JG, Edvardsson N

Clinical and translational science, 2021 Jun; 13(6):1336-1344

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First-in-Human Assessment of cRGD-ZW800-1, a Zwitterionic, Integrin-Targeted, Near-Infrared Fluorescent Peptide in Colon Carcinoma.

de Valk KS, Deken MM, Handgraaf HJM, Bhairosingh SS, Bijlstra OD, van Esdonk MJ, Terwisscha van Scheltinga AGT, Valentijn ARPM, March TL, Vuijk J, Peeters KCMJ, Holman FA, Hilling DE, Mieog JSD, Frangioni JV, Burggraaf J, Vahrmeijer AL

Clinical cancer research : an official journal of the American Association for Cancer Research, 2021 Jun; 26(15):3990-3998

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Brain Bio-Energetic State Does Not Correlate to Muscle Mitochondrial Function in Huntington's Disease.

van Diemen MPJ, Hart EP, Hameeteman PW, Coppen EM, Winder JY, den Heijer J, Moerland M, Kan H, van der Grond J, Webb A, Roos RAC, Groeneveld GJ

Journal of Huntington's disease, 2021 Jun; 9(4):335-344

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