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Stimulation of the PD-1 Pathway Decreases Atherosclerotic Lesion Development in Ldlr Deficient Mice

Hendrika W. Grievink, Virginia Smit, Robin A. F. Verwilligen, Mireia N. A. Bernabé Kleijn, Diede Smeets, Christoph J. Binder, Hideo Yagita, Matthijs Moerland, Johan Kuiper, Ilze Bot and Amanda C. Foks

Front. Cardiovasc. Med., 2021 Nov

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MTORC1 signaling as a biomarker in major depressive disorder and its pharmacological modulation by novel rapid-acting antidepressants

T. Cholewinski, D. Pereira, M. Moerland, G. Jacobs

Therapeutic Advances in Psychopharmacology, 2021 Oct

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Side-by-Side Comparison of uPAR-Targeting Optical Imaging Antibodies and Antibody Fragments for Fluorescence-Guided Surgery of Solid Tumors.

Baart VM, van Manen L, Bhairosingh SS, Vuijk FA, Iamele L, de Jonge H, Scotti C, Resnati M, Cordfunke RA, Kuppen PJK, Mazar AP, Burggraaf J, Vahrmeijer AL, Sier CFM

Molecular imaging and biology, 2021 Oct

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Fluorescence-guided surgery in colorectal cancer; A review on clinical results and future perspectives.

Galema HA, Meijer RPJ, Lauwerends LJ, Verhoef C, Burggraaf J, Vahrmeijer AL, Hutteman M, Keereweer S, Hilling DE

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2021 Oct

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Poloxamer 188 vs Placebo for Painful Vaso-occlusive Episodes in Children and Adults With Sickle Cell Disease.

Kenter MJH, Cohen AF

JAMA, 2021 Oct; 326(10):974-975

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Saliva as a sampling matrix for therapeutic drug monitoring of gentamicin in neonates: A prospective population pharmacokinetic and simulation study.

Samb A, Kruizinga M, Tallahi Y, van Esdonk M, van Heel W, Driessen G, Bijleveld Y, Stuurman R, Cohen A, van Kaam A, de Haan T, Mathôt R

British journal of clinical pharmacology, 2021 Oct

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Administration of an adeno-associated viral vector expressing interferon-β in patients with inflammatory hand arthritis, results of a phase I/II study.

Vrouwe JPM, Meulenberg JJM, Klarenbeek NB, Cañete AN, Reijnierse M, Ruiterkamp G, Bevaart L, Lamers RJ, Kloppenburg M, Nelissen RGHH, Huizinga TWJ, Burggraaf J, Kamerling IMC

Osteoarthritis and cartilage, 2021 Oct

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An exploratory first-in-man study to investigate the pharmacokinetics and safety of liposomal dexamethasone at a 2- and 1-week interval in patients with metastatic castration resistant prostate cancer.

Vrouwe JPM, Kamerling IMC, van Esdonk MJ, Metselaar JM, Stuurman FE, van der Pluijm G, Burggraaf J, Osanto S

Pharmacology research & perspectives, 2021 Oct; 9(5):e00845

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Challenges and opportunities of pharmacological interventions for osteoarthritis: A review of current clinical trials and developments

J.P.M.Vrouwe, J.Burggraaf, M.Kloppenburg, F.E.Stuurman

Osteoarthritis and Cartilage Open, 2021 Sep

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