Key publication
893
Therapeutic Areas
Methods & challenges

Key publication

Pharmacodynamic and pharmacokinetic effects of the intravenous CB1 receptor agonist Org 26828 in healthy male volunteers.

Key publication

Central nervous system effects of haloperidol on THC in healthy male volunteers.

Key publication

The effects of the glycine reuptake inhibitor R213129 on the central nervous system and on scopolamine-induced impairments in psychomotor and cognitive function in healthy subjects.

Key publication

Risk assessment in extrapolation of pharmacokinetics from preclinical data to humans.

Key publication

Acceptable risks and burdens for children in research without direct benefit: a systematic analysis of the decisions made by the Dutch Central Committee.

Key publication

Clinical pharmacology: a declaration of intent.

Key publication

Dabigatran etexilate.

Key publication

Sapropterin.

Key publication

Orexin receptor antagonism, a new sleep-promoting paradigm: an ascending single-dose study with almorexant.