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The CHDR library contains a wealth of research and innovative publications that pushes our quality of work towards the highest standards.
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  • An exploratory first-in-man study to investigate the pharmacokinetics and safety of liposomal dexamethasone at a 2- and 1-week interval in patients with metastatic castration resistant prostate cancer.

    Vrouwe JPM, Kamerling IMC, van Esdonk MJ, Metselaar JM, Stuurman FE, van der Pluijm G, Burggraaf J, Osanto S

    Pharmacology research & perspectives, 2021 Oct; 9(5):e00845

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  • Challenges and opportunities of pharmacological interventions for osteoarthritis: A review of current clinical trials and developments

    J.P.M.Vrouwe, J.Burggraaf, M.Kloppenburg, F.E.Stuurman

    Osteoarthritis and Cartilage Open, 2021 Sep

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  • Fundamentals and developments in fluorescence-guided cancer surgery.

    Mieog JSD, Achterberg FB, Zlitni A, Hutteman M, Burggraaf J, Swijnenburg RJ, Gioux S, Vahrmeijer AL

    Nature reviews. Clinical oncology, 2021 Sep

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  • Detection of cutaneous oxygen saturation using a novel snapshot hyperspectral camera: a feasibility study.

    van Manen L, Birkhoff WAJ, Eggermont J, Hoveling RJM, Nicklin P, Burggraaf J, Wilson R, Mieog JSD, Robinson DJ, Vahrmeijer AL, Bradbury MS, Dijkstra J

    Quantitative imaging in medicine and surgery, 2021 Sep; 11(9):3966-3977

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  • Intra-operative assessment of the vascularisation of a cross section of the meniscus using near-infrared fluorescence imaging.

    van Schie P, van der Lelij TJN, Gerritsen M, Meijer RPJ, van Arkel ERA, Fiocco M, Swen JA, Vahrmeijer AL, Hazelbag HM, Keereweer S, van Driel PBAA

    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2021 Aug

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  • Theoretical Performance of Nonlinear Mixed-Effect Models Incorporating Saliva as an Alternative Sampling Matrix for Therapeutic Drug Monitoring in Pediatrics: A Simulation Study.

    Kruizinga MD, Stuurman FE, Driessen GJA, Cohen AF, Bergmann KR, van Esdonk MJ

    Therapeutic drug monitoring, 2021 Aug; 43(4):546-554

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  • Effect of hydroxychloroquine on the cardiac ventricular repolarization - a randomized clinical trial.

    Eveleens Maarse BC, Graff C, Kanters JK, van Esdonk MJ, Kemme MJB, In 't Veld AE, Jansen MAA, Moerland M, Gal P

    British journal of clinical pharmacology, 2021 Jul

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  • Intradermal lipopolysaccharide challenge as an acute in vivo inflammatory model in healthy volunteers.

    Buters TP, Hameeteman PW, Jansen IME, van Hindevoort FC, Ten Voorde W, Florencia E, Osse M, de Kam ML, Grievink HW, Schoonakker M, Patel AA, Yona S, Gilroy DW, Lubberts E, Damman J, Feiss G, Rissmann R, Jansen MAA, Burggraaf J, Moerland M

    British journal of clinical pharmacology, 2021 Jul

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  • Dealing with doping. A plea for better science, governance and education.

    Heuberger JAAC, Henning A, Cohen AF, Kayser B

    British journal of clinical pharmacology, 2021 Jul

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Browse 965 publications in the CHDR library

  • Clinical studies & Development
  • CHDR's story
  • People
  • Education
  • Library

Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
    • Psychiatry
    • Sleep disorders

    Immunology & Inflammation

    • Immuno-Inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- & microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessements
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac & Endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Pharmacokinetics and pharmacometrics
    • CHDR Cardiology
    • Biomarker Laboratory
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 965 publications in the CHDR library

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