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Decreased integrity of the monoaminergic tract is associated with a positive response to MPH in patients with vascular cognitive impairment - proof of principle study STREAM-VCI.

Leijenaar JF, Ingala S, Sudre CH, Mutsaerts HM, Leeuwis AE, van der Flier WM, Scheltens P, Weinstein HC, Barkhof F, van Gerven J, Groeneveld GJ, Prins ND

Cerebral circulation - cognition and behavior, 2023 May

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Impact of oral administration of single strain spp. on immune responses to keyhole limpet hemocyanin immunization and gut microbiota: A randomized placebo-controlled trial in healthy volunteers.

Saghari M, Gal P, Grievink HW, Klaassen ES, Itano A, McHale D, Moerland M

Frontiers in immunology, 2023 May

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Analysis and visualization of the course and burden over time of adverse drug reactions (ADRs) attributed to TNFα-inhibitors in patients with inflammatory rheumatic diseases (IRDs).

de Boer M, Gosselt HR, Jansen J, van Doorn MBA, Hoentjen F, Nurmohamed MT, Spuls PI, Tas SW, Vonkeman HE, Jessurun NT

Expert opinion on drug safety, 2023 Mar; 22(3):195-202

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A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsis.

Liu F, Aulin LBS, Kossen SSA, Cathalina J, Bremmer M, Foks AC, van der Graaf PH, Moerland M, van Hasselt JGC

Journal of pharmacokinetics and pharmacodynamics, 2022 Oct

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Monitoring of Ex vivo Cyclosporin A Activity in Healthy Volunteers Using T Cell Function Assays in Relation to Whole Blood and Cellular Pharmacokinetics

Aliede E. in ’t Veld, Manon A. A. Jansen, Bertine W. Huisman, Mascha Schoonakker, Marieke L. de Kam, Dirk Jan A. R. Moes, Mariëtte I. E. van Poelgeest, Jacobus Burggraaf and Matthijss Moerland

Pharmaceutics, 2022 Sep

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Characterization of KLH-driven immune responses in clinical studies: A systematic review

Mahdi Saghari, Manon A. A. Jansen, Hendrika W. Grievink, Robert Rissmann, Matthijs Moerland

Front. Drug. Discov, 2022 Sep

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Lectin and alternative complement pathway activation in cutaneous manifestations of IgA-vasculitis: A new target for therapy?

Damman J, Mooyaart AL, Bosch TPPVD, Seelen MA, Doorn MBV

Molecular immunology, 2022 Mar

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Intradermal lipopolysaccharide challenge as an acute in vivo inflammatory model in healthy volunteers.

Buters TP, Hameeteman PW, Jansen IME, van Hindevoort FC, Ten Voorde W, Florencia E, Osse M, de Kam ML, Grievink HW, Schoonakker M, Patel AA, Yona S, Gilroy DW, Lubberts E, Damman J, Feiss G, Rissmann R, Jansen MAA, Burggraaf J, Moerland M

British journal of clinical pharmacology, 2021 Jul

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A randomized controlled trial with a delayed-type hypersensitivity model using keyhole limpet haemocyanin to evaluate adaptive immune responses in man.

Saghari M, Gal P, Ziagkos D, Burggraaf J, Powell JF, Brennan N, Rissmann R, van Doorn MBA, Moerland M

British journal of clinical pharmacology, 2020 Oct

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