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  • Inter- and intra-day variability in β-glucocerebrosidase activity and pathway biomarkers in healthy volunteers and patients with Parkinson’s disease with a GBA1 mutation

    Jurrian P. van der Valk, Daniël B. Dumas, Eva Thijssen , Diana R. Pereira, Wieke Grievink, Yalçin Yavuz, Cedric Pesch, Daniel Ysselstein, Mackenzie Hagey, Omer Siddiqui, Jesse M. Cedarbaum, Kevin W. Hunt, Philip H.C. Kremer

    Download poster (PDF, 621.09 kb)

  • Effects of levetiracetam in patients with generalized epilepsy on Transcranial Magnetic Stimulation

    CatherineM.E. de Cuba, Marjet L. Claessens, Titia Q. Ruijs, Annika A. de Goede, Robert J. Doll, Michel J.A.M. van Putten, Geert Jan Groeneveld, Jules A.A.C. Heuberger

    Download poster (PDF, 338.45 kb)

  • Effects of the selective sphingosine-1-phosphate subtype 1 receptor modulator, TRV045, on cortical excitability using resting-state EEG and transcranial magnetic stimulation 

    Catherine M.K.E. de Cuba1,2, Annika A. de Goede1, Erica Klaassen1, Robert J. Doll1, Geert Jan Groeneveld1,2, Jessica Kim3, Mark A. Demitrack3, Jules A.A.C. Heuberger1 

    Download poster (PDF, 367.84 kb)

  • MDMA for Posttraumatic Stress Disorder: A Narrative Review Highlighting 5-HT Mediated Neuroplasticity

    S. Makai-Bölöni, T.P.L. Bostoen, J.M.A. van Gerven, G.E. Jacobs

    Download poster (PPTX, 1.73 mb)

  • Effects of sodium channel blockers on “nerve excitability threshold tracking”

    T.Q. Ruijs, J.A.A.C. Heuberger, I. Koopmans, M. de Kam, M. van Esdonk, G.J. Groeneveld

    Download poster (PDF, 401.36 kb)

  • Safety, Pharmacokinetics and Target Engagement of novel RIPK1 inhibitor SAR443060 (DNL747) in Patients with Amyotrophic Lateral Sclerosis

    Maurits F J M Vissers, Jules A A C Heuberger, R Tsai, R Erickson, A Cruz-Herrranz, J Harris, F Huang, V Tong, Y Zhu, K Scearce-Levie, J Hsiao-Nakamoto, X Tang, C McKenna, C Ho, MD Troyer, R.J. Pomponio, M. Alonso-Alonso, M. Zilberstein, N. Atassi, Geert Jan Groeneveld

    Download poster (PDF, 229.84 kb)

  • Fatty acids and Glucocerebrosidase activity as potential biomarkers of stearyl-CoA desaturase inhibition; an observational study of inter- and intraday variation in healthy volunteers and patients with Parkinson's disease.

    P.P.N.M Eijsvogel, A.A. Gorbenko, D. Tardiff, M. Skupien, K. Rhodes, R. Scannevin, M. de Kam, P.H.K. Kremer, E.M.J. van Brummelen, B. Robertson, G.J. Groeneveld

    Download poster (PDF, 375.23 kb)

  • Estimation of the clinical severity of Facioscapulohumeral Muscular Dystrophy (FSHD) using smartphone and remote monitoring sensor data

    Ahnjili Zhuparris, Ghobad Maleki, Ingrid Koopmans, Nicole Voet, Otto Postma, Adam Cohen, Emilie van Brummelen, Robert-Jan Doll, Joris De Maeyer, Geert Jan Groeneveld

    Download poster (PDF, 712.01 kb)

  • Transcranial Magnetic Stimulation as a Translational Biomarker for Modulation of AMPA Receptor Function

    Patricio O’Donnell, Francis Dijkstra, Ugur Damar, Andres Pascual-Leone, Quanhong Lei, Annika de Goede, Lin Xu, Derek L. Buhl, Rob Zuiker,Titia Ruijs, Martin Lubell, Mahnaz Asgharnejad, Venkatesha Murthy, Alexander Rotenberg, Gabriel Jacobs, Laura Rosen

    Download poster (PDF, 1.42 mb)

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Browse 1148 publications in the CHDR library

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Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
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    Immunology & Inflammation

    • Immuno-inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- and microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
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  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessments
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac and endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Biomarker Engineering and Analytics
    • Biomarker Laboratory
    • Cardiology Services
    • Pharmacokinetics and pharmacometrics
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 1148 publications in the CHDR library

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