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  • Safety, tolerability and pharmacokinetic characterisation of DACRA KBP-042 in healthy male subjects.

    Henriksen K, Broekhuizen K, de Boon WMI, Karsdal MA, Bihlet AR, Christiansen C, Dillingh MR, de Kam M, Kumar R, Burggraaf K, Kamerling IMC

    British journal of clinical pharmacology, 2021 May

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  • Additive effect of erythropoietin use on exercise-induced endothelial activation and hypercoagulability in athletes.

    Heuberger JAAC, Posthuma JJ, Ziagkos D, Rotmans JI, Daniels JMA, Gal P, Stuurman FE, Spronk HMH, Ten Cate H, Burggraaf J, Moerland M, Cohen AF

    European journal of applied physiology, 2020 Aug; 120(8):1893-1904

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  • Model informed quantification of the feed-forward stimulation of growth hormone by growth hormone-releasing hormone.

    van Esdonk MJ, Burggraaf J, van der Graaf PH, Stevens J

    British journal of clinical pharmacology, 2020 Mar

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  • A two-step deconvolution-analysis-informed population pharmacodynamic modeling approach for drugs targeting pulsatile endogenous compounds.

    van Esdonk MJ, Burggraaf J, van der Graaf PH, Stevens J

    Journal of pharmacokinetics and pharmacodynamics, 2019 Mar; 44(4):389-400

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  • A Novel Somatostatin-Dopamine Chimera (BIM23B065) Reduced GH Secretion in a First-in-Human Clinical Trial.

    de Boon WMI, van Esdonk MJ, Stuurman FE, Biermasz NR, Pons L, Paty I, Burggraaf J

    The Journal of clinical endocrinology and metabolism, 2019 Mar; 104(3):883-891

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  • Renal Effects of Antisense-Mediated Inhibition of SGLT2.

    van Meer L, Moerland M, van Dongen M, Goulouze B, de Kam M, Klaassen E, Cohen A, Burggraaf J

    The Journal of pharmacology and experimental therapeutics, 2016 Oct; 359(2):280-289

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  • Changes in bone mineral density in newly diagnosed testicular cancer patients after anticancer treatment.

    Willemse PM, Hamdy NA, de Kam ML, Burggraaf J, Osanto S

    The Journal of clinical endocrinology and metabolism, 2014 Oct; 99(11):4101-8

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  • Comparison of body surface area versus weight-based growth hormone dosing for girls with Turner syndrome.

    Schrier L, de Kam ML, McKinnon R, Che Bakri A, Oostdijk W, Sas TC, Menke LA, Otten BJ, de Muinck Keizer-Schrama SM, Kristrom B, Ankarberg-Lindgren C, Burggraaf J, Albertsson-Wikland K, Wit JM

    Hormone research in paediatrics, 2014 Mar; 81(5):319-30

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  • Obesity is associated with an altered autonomic nervous system response to nutrient restriction.

    Wijngaarden MA, Pijl H, van Dijk KW, Klaassen ES, Burggraaf J

    Clinical endocrinology, 2013 Oct; 79(5):648-51

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Browse 1019 publications in the CHDR library

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Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
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    • Immuno-inflammation
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    Cardiovascular & Metabolic disease

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    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
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  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessments
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac and endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Biomarker Laboratory
    • Cardiology Services
    • Pharmacokinetics and pharmacometrics
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 1019 publications in the CHDR library

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