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Effect of changes in liver blood flow on the pharmacokinetics of saruplase in patients with acute myocardial infarction.

van Griensven JM, Koster RW, Hopkins GR, Beier H, Günzler WA, Kroon R, Schoemaker RC, Cohen AF

Thrombosis and haemostasis, 1997 Aug; 78(3):1015-20

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Pharmacokinetics of saruplase, a recombinant unglycosylated human single-chain urokinase-type plasminogen activator and its effects on fibrinolytic and haemostatic parameters in healthy male subjects.

de Boer A, Kluft C, Gerloff J, Dooijewaard G, Günzler WA, Beier H, van der Meer FJ, Cohen AF

Thrombosis and haemostasis, 1993 Aug; 70(2):320-5

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Plasmin inhibitors in the prevention of systemic effects during thrombolytic therapy: specific role of the plasminogen-binding form of alpha 2-antiplasmin.

Leebeek FW, Kluft C, Knot EA, Los P, Cohen AF, Six AJ

Journal of the American College of Cardiology, 1990 May; 15(6):1212-20

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Interaction study between Org 10172, a low molecular weight heparinoid, and acetylsalicylic acid in healthy male volunteers.

de Boer A, Danhof M, Cohen AF, Magnani HN, Breimer DD

Thrombosis and haemostasis, 1991 Jul; 66(2):202-7

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Introduction to haemostasis from a pharmacodynamic perspective.

Kluft C, Burggraaf J

British journal of clinical pharmacology, 2011 Sep; 72(4):538-46

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Safety and dose-dependency of eptacog beta (activated) in a dose escalation study of non-bleeding congenital haemophilia A or B patients, with or without inhibitors.

Ducore J, Lawrence JB, Simpson M, Boggio L, Bellon A, Burggraaf J, Stevens J, Moerland M, Frieling J, Reijers J, Wang M

Haemophilia : the official journal of the World Federation of Hemophilia, 2018 Feb; 23(6):844-851

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Pharmacodynamics and pharmacokinetics of the novel thrombopoietin mimetic peptide RWJ-800088 in humans.

Liem-Moolenaar M, Cerneus D, Molloy CJ, End D, Brown KH, de Kam ML, Cohen AF, van Hensbergen Y, Burggraaf J

Clinical pharmacology and therapeutics, 2008 Sep; 84(4):481-7

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Effect of isotretinoin on endogenous tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1) in humans.

Wallnöfer AE, van Griensven JM, Schoemaker HC, Cohen AF, Lambert W, Kluft C, Meijer P, Kooistra T

Thrombosis and haemostasis, 1993 Dec; 70(6):1005-8

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Pharmacokinetics and pharmacodynamics of saruplase, an unglycosylated single-chain urokinase-type plasminogen activator, in patients with acute myocardial infarction.

Koster RW, Cohen AF, Hopkins GR, Beier H, Günzler WA, van der Wouw PA

Thrombosis and haemostasis, 1994 Oct; 72(5):740-4

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