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CNS-related performance and haemodynamics of metoprolol-Oros and propranolol after single and 3 days dosing in healthy volunteers.

van Steveninck AL, Pieters MS, Schoemaker HC, Breimer DD, Cohen AF

British journal of clinical pharmacology, 1993 Jan; 35(2):114-20

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The bioavailability of digoxin from three oral formulations measured by a specific h.p.l.c. assay.

Cohen AF, Kroon R, Schoemaker HC, Breimer DD, Van Vliet-Verbeek A, Brandenburg HC

British journal of clinical pharmacology, 1993 Jan; 35(2):136-42

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Characterization of glutathione conjugation in humans: stereoselectivity in plasma elimination pharmacokinetics and urinary excretion of (R)- and (S)-2-bromoisovalerylurea in healthy volunteers.

Mulders TM, Venizelos V, Schoemaker R, Cohen AF, Breimer DD, Mulder GJ

Clinical pharmacology and therapeutics, 1992 Dec; 53(1):49-58

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Influence of heparin and a low molecular weight heparinoid on specific endogenous and exogenous fibrinolytic factors during rest and exercise.

de Boer A, Kluft C, Dooijewaard G, Kasper FJ, Kroon JM, Breimer DD, Stiekema JC, Cohen AF

Thrombosis and haemostasis, 1992 Nov; 68(5):550-5

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Highly variable anticoagulant response after subcutaneous administration of high-dose (12,500 IU) heparin in patients with myocardial infarction and healthy volunteers.

Kroon C, ten Hove WR, de Boer A, Kroon JM, van der Pol JM, Harthoorn-Lasthuizen EJ, Schoemaker HC, van der Meer FJ, Cohen AF

Circulation, 1992 Oct; 86(5):1370-5

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Effects of temazepam on saccadic eye movements: concentration-effect relationships in individual volunteers.

van Steveninck AL, Verver S, Schoemaker HC, Pieters MS, Kroon R, Breimer DD, Cohen AF

Clinical pharmacology and therapeutics, 1992 Sep; 52(4):402-8

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Diurnal rhythm in anticoagulant effect of heparin during a low dose constant rate infusion. A study in healthy volunteers.

Krulder JW, de Boer A, van den Besselaar AM, Cohen AF, Schoemaker HC, Briët E, Meinders AE

Thrombosis and haemostasis, 1992 Jul; 68(1):30-2

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Pronounced effects of the combination of a new thromboxane antagonist (GR32191) and heparin on bleeding time in man.

de Boer A, Kroon JM, Kroon C, van Vliet A, Schoemaker HC, Breimer DD, Donoghue S, Cohen AF

Thrombosis and haemostasis, 1992 Jul; 68(1):24-9

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Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite alpha-hydroxymidazolam in healthy volunteers.

Mandema JW, Tuk B, van Steveninck AL, Breimer DD, Cohen AF, Danhof M

Clinical pharmacology and therapeutics, 1992 May; 51(6):715-28

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