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The CHDR library contains a wealth of research and innovative publications that pushes our quality of work towards the highest standards.
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  • Biperiden Challenge Model in Healthy Elderly as Proof-of-pharmacology Tool; A Randomized Placebo-controlled Trial.

    Bakker C, van Esdonk MJ, Stuurman RFE, Borghans LAGJM, de Kam ML, van Gerven JMA, Groeneveld GJ

    Journal of clinical pharmacology, 2021 May

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  • Safety, tolerability and pharmacokinetic characterisation of DACRA KBP-042 in healthy male subjects.

    Henriksen K, Broekhuizen K, de Boon WMI, Karsdal MA, Bihlet AR, Christiansen C, Dillingh MR, de Kam M, Kumar R, Burggraaf K, Kamerling IMC

    British journal of clinical pharmacology, 2021 May

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  • Intronic Haplotypes in GBA Modify Age at Diagnosis of Parkinson's: Replication in a Subgroup

    Justin M. O'Sullivan, Jonas M. den Heijer, Geert J. Groeneveld, Antony A. Cooper

    Movement disorders, 2021 May

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  • Postdischarge Recovery after Acute Pediatric Lung Disease Can Be Quantified with Digital Biomarkers.

    Kruizinga MD, Moll A, Zhuparris A, Ziagkos D, Stuurman FE, Nuijsink M, Cohen AF, Driessen GJA

    Respiration; international review of thoracic diseases, 2021 May

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  • Using machine learning techniques to characterize sleep-deprived driving behavior.

    van der Wall HEC, Doll RJ, van Westen GJP, Koopmans I, Zuiker RG, Burggraaf J, Cohen AF

    Traffic injury prevention, 2021 May

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  • Good Clinical Trials by removing defensive interpretation of Good Clinical Practice guidelines

    Jonas M. den Heijer, Jules A. A. C. Heuberger, Hemme Hijma, Annelieke C. Kruithof, Jeroen van Smeden, Geert Jan Groeneveld, Jacobus Burggraaf, Adam Cohen

    Brit Jnl Clinical Pharma. , 2021 May

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  • Development and Technical Validation of a Smartphone-Based Cry Detection Algorithm.

    ZhuParris A, Kruizinga MD, van Gent M, Dessing E, Exadaktylos V, Doll RJ, Stuurman FE, Driessen GA, Cohen AF

    Frontiers in pediatrics, 2021 May

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  • Stability analysis of clustering of Norris' visual analogue scale: Applying the consensus clustering approach.

    Guan Z, Chen XG, Hay J, van Gerven J, Burggraaf J, de Kam M

    Medicine, 2021 Apr; 100(17):e25363

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  • Phase 1 Clinical Trial of Losmapimod in Facioscapulohumeral Dystrophy (FSHD): Safety, Tolerability, Pharmacokinetics, and Target Engagement.

    Mellion ML, Ronco L, Berends CL, Pagan L, Brooks S, van Esdonk MJ, van Brummelen EMJ, Odueyungbo A, Thompson LA, Hage M, Badrising UA, Raines S, Tracewell WG, van Engelen B, Cadavid D, Groeneveld GJ

    British journal of clinical pharmacology, 2021 Apr

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Browse 969 publications in the CHDR library

  • Clinical studies & Development
  • CHDR's story
  • People
  • Education
  • Library

Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
    • Psychiatry
    • Sleep disorders

    Immunology & Inflammation

    • Immuno-Inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- & microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessements
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac & Endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Pharmacokinetics and pharmacometrics
    • CHDR Cardiology
    • Biomarker Laboratory
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 969 publications in the CHDR library

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