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The Effect of a 13-Valent Conjugate Pneumococcal Vaccine on Circulating Antibodies Against Oxidized LDL and Phosphorylcholine in Man, A Randomized Placebo-Controlled Clinical Trial

Hendrika W. Grievink, Pim Gal, Maria Ozsvar Kozma, Erica S. Klaassen, Johan Kuiper, Jacobus Burggraaf, Christoph J. Binder, and Matthijs Moerland

biology, 2020 Oct

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Safety, pharmacokinetics, and pharmacodynamics of Gln‐1062, a prodrug of galantamine

Charlotte Bakker, Jasper van der Aart, Ellen P. Hart, Erica S. Klaassen, Kirsten R. Bergmann, Michiel J. van Esdonk, Denis G. Kay, Geert Jan Groeneveld

Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2020 Oct

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Dose-Finding Study of a CEA-Targeting Agent, SGM-101, for Intraoperative Fluorescence Imaging of Colorectal Cancer.

de Valk KS, Deken MM, Schaap DP, Meijer RP, Boogerd LS, Hoogstins CE, van der Valk MJ, Kamerling IM, Bhairosingh SS, Framery B, Hilling DE, Peeters KC, Holman FA, Kusters M, Rutten HJ, Cailler F, Burggraaf J, Vahrmeijer AL

Annals of surgical oncology, 2020 Oct

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Near-infrared fluorescence imaging compared to standard sentinel lymph node detection with blue dye in patients with vulvar cancer - a randomized controlled trial.

Deken MM, van Doorn HC, Verver D, Boogerd LSF, de Valk KS, Rietbergen DDD, van Poelgeest MIE, de Kroon CD, Beltman JJ, van Leeuwen FWB, Putter H, Braak JPBM, de Geus-Oei LF, van de Velde CJH, Burggraaf J, Vahrmeijer AL, Gaarenstroom KN

Gynecologic oncology, 2020 Oct

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A randomized controlled trial with a delayed-type hypersensitivity model using keyhole limpet haemocyanin to evaluate adaptive immune responses in man.

Saghari M, Gal P, Ziagkos D, Burggraaf J, Powell JF, Brennan N, Rissmann R, van Doorn MBA, Moerland M

British journal of clinical pharmacology, 2020 Oct

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Topical anti-microbial peptide omiganan recovers cutaneous dysbiosis but does not improve clinical symptoms in patients with mild-to-moderate atopic dermatitis in a phase 2 randomized controlled trial.

van der Kolk TN, Buters TP, Krouwels L, Boltjes J, de Kam ML, van der Wall H, van Alewijk DCJG, van den Munckhof EHA, Becker MJ, Feiss G, Florencia EF, Prens EP, Moerland M, Burggraaf J, Rissmann R, van Doorn MBA

Journal of the American Academy of Dermatology, 2020 Sep

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Development of Novel, Value-Based, Digital Endpoints for Clinical Trials: A Structured Approach Toward Fit-for-Purpose Validation

M. D. Kruizinga, F. E. Stuurman, V. Exadaktylos, R. J. Doll, D. T. Stephenson, G. J. Groeneveld, G. J. A. Driessen and A. F. Cohen

Pharmacological Reviews, 2020 Sep

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How to expedite early-phase SARS-CoV-2 vaccine trials in pandemic setting-A practical perspective

Johan L van der Plas, Meta Roestenberg, Adam F Cohen, Ingrid M C Kamerling

Br J Clin Pharmacol, 2020 Sep

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Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans.

Salvadore G, Bonaventure P, Shekhar A, Johnson PL, Lord B, Shireman BT, Lebold TP, Nepomuceno D, Dugovic C, Brooks S, Zuiker R, Bleys C, Tatikola K, Remmerie B, Jacobs GE, Schruers K, Moyer J, Nash A, Van Nueten LGM, Drevets WC

Translational psychiatry, 2020 Sep; 10(1):308

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