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Translatability of preclinical to early clinical tolerable and pharmacologically active dose ranges for central nervous system active drugs.

Ferreira GS, Dijkstra FM, Veening-Griffioen DH, Boon WPC, Schellekens H, Moors EHM, van Meer PJK, Stuurman FE, van Gerven JMA

Translational psychiatry, 2023 Mar; 13(1):74

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Analysis and visualization of the course and burden over time of adverse drug reactions (ADRs) attributed to TNFα-inhibitors in patients with inflammatory rheumatic diseases (IRDs).

de Boer M, Gosselt HR, Jansen J, van Doorn MBA, Hoentjen F, Nurmohamed MT, Spuls PI, Tas SW, Vonkeman HE, Jessurun NT

Expert opinion on drug safety, 2023 Mar; 22(3):195-202

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LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's Disease

D. Jennings, S. Huntwork-Rodriguez, M.F.J.M. Vissers, V.M. Daryani, D. Diaz, M.S. Goo, J.J. Chen, R. Maciuca, K. Fraser, O.A. Mabrouk, J. van de Wetering de Rooij, J.A.A.C. Heuberger, G.J. Groeneveld, M. T Borin, A. Cruz-Herranz, D. Graham, K. Scearce-Levie, J. De Vicente, A. G. Henry, P. Chin, C. Ho, M.D. Troyer

Official Journal of the International Parkinson and Movement Disorder Society, 2023 Feb

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Antidepressants as a potential candidate to reduce microglia activation in neurodegenerative diseases. A systematic review and meta-analysis of preclinical studies

Lisa Nicolai, Pauline Nettesheim, Lot D. de Witte, Gijsje Snijders

Journal of Affective Disorders Reports, 2023 Feb

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The Benefit of Complete Response to Treatment in Patients With Chronic Spontaneous Urticaria-CURE Results.

Kolkhir P, Laires PA, Salameh P, Asero R, Bizjak M, Košnik M, Dissemond J, van Doorn M, Hawro T, Kasperska-Zajac A, Zajac M, Kocatürk E, Peter J, Parisi CAS, Ritchie CA, Kulthanan K, Tuchinda P, Fomina D, Kovalkova E, Khoshkhui M, Kouzegaran S, Papapostolou N, Du-Thanh A, Kamegashira A, Meshkova R, Vitchuk A, Bauer A, Grattan C, Staubach P, Bouillet L, Giménez-Arnau AM, Maurer M, Weller K

The journal of allergy and clinical immunology. In practice, 2023 Feb; 11(2):610-620.e5

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Data-Driven Identification of Targets for Fluorescence-Guided Surgery in Non-Small Cell Lung Cancer.

Meijer RPJ, Neijenhuis LKA, Zeilstra AP, Roerink SF, Bhairosingh SS, Hilling DE, Mieog JSD, Kuppen PJK, Sier CFM, Braun J, Burggraaf J, Vahrmeijer AL, Cohen D, Hutteman M

Molecular imaging and biology, 2023 Feb; 25(1):228-239

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Risk of osteoporosis in testicular germ cell tumour survivors: A systematic review of the literature.

Vrouwe JPM, Hennus PML, Hamdy NAT, Osanto S, Willemse PM

BJUI compass, 2023 Jan; 4(1):24-43

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Repeated intravenous esketamine treatment in patients with ECT-resistant major depressive disorder

A. Safai Pour a b 1, S.J.M. van der Aalst a 1, I.J. Brouwer a, E.J. Giltay a, G.E. Jacobs a b, N.J.A. van der Wee a, A.M. van Hemert a, M.S. van Noorden

Journal of Affective Disorders Reports Volume 10, December 2022, 100400, 2022 Dec

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Randomized, double-blind, placebo-controlled study to characterize the immune response after repeated Keyhole Limpet Hemocyanin immunizations in healthy volunteers

M.N. Ronner, M.A.A. Jansen, M. Saghari, H.W. Grievink, N.B. Klarenbeek, S. Arif, M. Moerland

2022 Dec

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