Key publication
937
Therapeutic Areas
Methods & challenges

Key publication

Colistin resistance dynamics in under biofilm and planktonic growth.

Key publication

Identifying human toxicodynamic variability: A systematic evidence map of the current knowledge.

Key publication

Sentinel dosing: A proposed algorithm to guide decision making on which cohorts in early phase clinical pharmacology trials should use this approach.

Key publication

Correction: Preclinical evaluation of glycan-targeting monoclonal antibodies for bimodal near-infrared fluorescence and photoacoustic imaging of gastrointestinal cancers.

Key publication

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

Key publication

Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trial.

Key publication

Navigating adverse immunostimulation: A practical guide for clinical researchers

Key publication

Proof of Pharmacology, Safety, and Pharmacokinetics of the Novel TRPA1 Antagonist BI 1839100: A Randomized, Placebo-Controlled, Parallel Group, First-In-Human Study in Healthy Male Participants.

Key publication

Mild psoriasis as a suitable model for proof-of-mechanism in a phase 1B setting: Results from a double-blind placebo-controlled trial with guselkumab.