The role of motilin in the regulation of upper gastrointestinal (GI) motility is well defined. However, little is known about the effects on the distal GI tract. To investigate the effect of exogenous motilin on rectal function, barostat measurements in the rectum were performed and lower abdominal symptoms were scored.
The effect of motilin on the rectum in healthy volunteers.
CHDR
Kamerling IM, Burggraaf J, van Haarst AD, Oppenhuizen-Duinker MF, Schoemaker HC, Biemond I, Jones R, Heinzerling H, Cohen AF, Masclee AA
