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Reproducibility of biomarkers in induced sputum and in serum from chronic smokers.

31 July 2015. doid: 10.1016/j.pupt.2015.05.001

Zuiker RG, Kamerling IM, Morelli N, Calderon C, Boot JD, de Kam M, Diamant Z, Burggraaf J, Cohen AF

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Soluble inflammatory markers obtained from non-invasive airway sampling such as induced sputum may be useful biomarkers for targeted pharmaceutical interventions. However, before these soluble markers can be used as potential targets, their variability and reproducibility need to be established in distinct study populations.

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