Recovery of the acute hypoxic ventilatory response after reversal of a minimal neuromuscular block. A randomized, controlled trial in healthy, non-obese volunteers.

11 July 2025. doid: 10.1097/ALN.0000000000005650

Snoek MAJ, van Lemmen MA, van der Schrier R, van Velzen M, Dahan A, Boon M

Neuromuscular blocking agents inhibit the peripheral chemoreflex. We examined the effect of sugammadex 2 mg/kg and 4 mg/kg compared to spontaneous recovery of neuromuscular block (NMB) on the recovery of the acute hypoxic ventilatory response (AHVR).

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Recovery of the acute hypoxic ventilatory response after reversal of a minimal neuromuscular block. A randomized, controlled trial in healthy, non-obese volunteers.

Advancing the boundaries of clinical drug development