Interactions of sugammadex with various anticoagulants

Kruithof AC, Kluft C, de Kam PJ, Laterveer GH, Moerland M, Burggraaf J

To investigate in vitro the effect of sugammadex on activated partial thromboplastin time (APTT) and prothrombin time (PT) prolongations with various anticoagulants as well as the neutralizing effect of rocuronium and vecuronium on sugammadex effects on APTT and PT.