Development of an optimal furosemide infusion strategy in infants with modeling and simulation.

Schoemaker RC, van dDer Vorst MM, van Heel IR, Cohen AF, Burggraaf J,

The optimal dosing strategy for continuous intravenous furosemide infusion is unknown in pediatric patients. Eighteen patients less than 1 year old were studied after cardiac surgery during routine clinical care. The current strategy starts with a continuous infusion of 0.1 mg/kg x h, which may be adapted.