Transcranial magnetic stimulation (TMS) coupled with electromyography (EMG) and electroencephalography (EEG) has been evaluated at CHDR as a biomarker to study the clinical effects of drugs that are expected to affect cortical excitability. Both single-pulse and paired-pulse TMS stimulation protocols have been implemented at CHDR and can be customised according to study design.
Methodological rigour is ensured through the implementation of a standard operating procedure (SOP) which guides the performance of TMS-EMG and TMS-EEG assessments. Watch the video for a brief overview of the procedure.