We assessed whether total sleep deprivation (TSD) in combination with pain tests yields a reliable method to assess altered pain thresholds, which subsequently may be used to investigate (novel) analgesics in healthy subjects.
A crossover study evaluating the sex-dependent and sensitizing effects of sleep deprivation using a nociceptive test battery in healthy subjects.
CHDR
Hijma H, Koopmans I, Klaassen E, Doll RJ, Zuiker R, Groeneveld GJ
