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Characterization of the Pharmacokinetic and Pharmacodynamic Profile of Apraglutide, a Glucagon-Like Peptide-2 Analog, in Healthy Volunteers

Bolognani F, Kruithof AC, Schulthess P, Machacek M, de Kam ML, Bergmann KR, van Gent M, Moerland M, Crenn P, Greig G, Gal P

The Journal of pharmacology and experimental therapeutics, 2023 Jun

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Effect of sphingosine and phytosphingosine ceramide ratio on lipid arrangement and barrier function in skin lipid models.

Nădăban A, Rousel J, El Yachioui D, Gooris GS, Beddoes CM, Dalgliesh RM, Malfois M, Rissmann R, Bouwstra JA

Journal of lipid research, 2023 Jun

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Machine Learning Techniques for Developing Remotely Monitored Central Nervous System Biomarkers Using Wearable Sensors: A Narrative Literature Review

Ahnjili ZhuParris, Annika A. de Goede, Iris E. Yocarini, Wessel Kraaij, Geert Jan Groeneveld, and Robert Jan Doll

Sensors, 2023 Jun

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Decreased integrity of the monoaminergic tract is associated with a positive response to MPH in patients with vascular cognitive impairment - proof of principle study STREAM-VCI.

Leijenaar JF, Ingala S, Sudre CH, Mutsaerts HM, Leeuwis AE, van der Flier WM, Scheltens P, Weinstein HC, Barkhof F, van Gerven J, Groeneveld GJ, Prins ND

Cerebral circulation - cognition and behavior, 2023 May

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Objective Home-Monitoring of Physical Activity, Cardiovascular Parameters, and Sleep in Pediatric Obesity.

Knijff JM, Houdijk ECAM, van der Kaay DCM, van Berkel Y, Filippini L, Stuurman FE, Cohen AF, Driessen GJA, Kruizinga MD

Digital biomarkers, 2023 May; 6(1):19-29

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Increased Tacrolimus Exposure in Kidney Transplant Recipients With COVID-19: Inflammation-Driven Downregulation of Metabolism as a Potential Mechanism.

Klomp SD, Meziyerh S, Vissers MFJM, Moes DJAR, Arends EJ, Teng YKO, Swen JJ, de Vries APJ

Transplant international : official journal of the European Society for Organ Transplantation, 2023 May

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Impact of oral administration of single strain spp. on immune responses to keyhole limpet hemocyanin immunization and gut microbiota: A randomized placebo-controlled trial in healthy volunteers.

Saghari M, Gal P, Grievink HW, Klaassen ES, Itano A, McHale D, Moerland M

Frontiers in immunology, 2023 May

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Identification of peripheral vascular function measures and circulating biomarkers of mitochondrial function in patients with mitochondrial disease.

van Kraaij SJW, Pereira DR, Smal B, Summo L, Konkel A, Lossie J, Busjahn A, Grammatopoulos TN, Klaassen E, Fischer R, Schunck WH, Gal P, Moerland M

Clinical and translational science, 2023 May

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Pharmacological characterization of the selective orexin-1 receptor antagonist JNJ-61393215 in healthy volunteers.

Brooks S, Zuiker R, Bleys C, Ziagkos D, Moyer JA, van Nueten L, Bonaventure P, Drevets WC, van Gerven J, Salvadore G, Jacobs GE

Journal of psychopharmacology (Oxford, England), 2023 May

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