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Safety, tolerability and biological activity of repeated intranasal administration of TLR3 agonist Ampligen (Poly I:Poly C12U) in healthy subjects

Lisanne C.A. Smidt, Aliede E. in ’t Veld, Johan L. van der Plas, Christina Yfanti, Ingrid M.C. Kamerling, Naomi B. Klarenbeek, Diane L. Young, David R. Strayer, Manon A.A. Jansen, Matthijs Moerland

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Clinical, cellular and molecular effects of topical and systemic corticosteroids on the inflammatory response to intradermal lipopolysaccharide administration in healthy volunteers

Thomas P. Buters, Pieter Hameeteman, Iris Jansen, Floris van Hindevoort, Wouter ten Voorde, Marieke L. de Kam, Derek W. Gilroy, Gary Feiss, Robert Rissmann, Manon A.A. Jansen, Jacobus Burggraaf and Matthijs Moerland

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The intradermal LPS challenge as potential in vivo inflammasome model

J. van ’t Westende, T. Buters, W. Grievink, M.A.A. Jansen, P. Hameeteman, R. Rissmann, J. Burggraaf, M. Moerland

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Pharmacodynamic monitoring of cyclosporin A activity using ex vivo T cell function assays

A.E.in ‘t Veld, M.A.A.Jansen, B.W.Huisman, M.Schoonakker, M.L.de Kam, D.J.A.R.Moes, M.I.E.van Poelgeest, A.F.Cohen and M.Moerland

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Immunosuppression by hydroxychloroquine: mechanistic proof in in vitro experiments but limited systemic activity in a human clinical pharmacology study

A.E. in ‘t Veld, H.W. Grievink, J.L. van der Plas, B.C. Eveleens Maarse, B. van Kraaij, N.B. Klarenbeek, M.L. de Kam, M.A.A. Jansen, and M. Moerland

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Ampligen (Poly I:Poly C12U) as a potential COVID-19 treatment: safety and tolerability of repeated intranasal administration in healthy subjects

J. L. vd Plas, L.C.A. Smidt, A.E in 't Veld, C. Yfanti, I.M.C Kamerling, N.B. Klarenbeek, D.L. Young, D.R. Strayer, M.A.A. Jansen, M. Moerland

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Vaccination against Streptococcus pneumoniae induces IgM antibodies against oxidized LDL in mouse, but Prevenar vaccination does not in man

H.W. Grievink, P. Gal MD PhD, C.J. Binder MD PhD, M. Ozsvar Kozma, E. Klaassen MSc, J. Kuiper, J. Burggraaf MD PhD, M. Moerland PhD

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Immunomonitoring of of Tacrolimus in healthy volunteers: the first step from PK- to PD-based therapeutic drug monitoring

A.E. in 't Veld, H.W. Grievink, M. Saghari, F.E. Stuurman, M.L. de Kam, B.C.M. de Winter, J. Burggraaf, A.F. Cohen, M. Moerland

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Stimulation of the PD-1 pathway decreases atherosclerotic lesion development in LDLr-/- mice

H.W. Grievink, D. Smeets, N. Benne, R. Verwilligen, M. Moerland, J.Kuiper, I. Bot, A.C. Foks

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