- CHDR conducts clinical trials in dermatology in order to study targeted drug delivery and treatment of a wide range of dermatological conditions, including psoriasis, eczema, and premalignant lesions.
- The majority of our dermatology trials use Trial@home, our unique approach to outpatient research.
- Our customised, user-friendly apps for smartphones and tablets ensure patient compliance and help researchers monitor the lesion and the patient’s daily activities.
- The study compound can be applied topically transdermally, intradermally, or subcutaneously, and CHDR can study both local pharmacokinetics and the compound’s effects on the skin.
CHDR conducts clinical phase I/IIa trials for pharmaceuticals, medical devices, cosmetics, food supplements and consumer products entailing following types of studies:
Practical answers to important research questions
Does our compound treat the targeted skin condition?
Early in drug development, CHDR can collect a wealth of data regarding the compound’s intended and/or unintended effects, even in healthy subjects. This data-intensive approach facilitates rational decision-making regarding the course of drug development. In dermatology 3D photography, total body mapping of skin lesions, objective lesion quantification and other innovative measurements can serve as robust predictors of clinical efficacy.
How well is the compound absorbed, and how is it eliminated?
main areas of expertise, and CHDR researchers study systemic absorption in the initial clinical phases of drug development. This proactive approach allows researchers to minimise the risk of adverse systemic effects in subsequent trials, which is particularly important when patients apply the compound at home.
Does our compound have anti-inflammatory properties?
In recent years, CHDR has selected and validated a comprehensive panel of biomarkers for measuring inflammation ex vivo. In addition, we have developed several pharmacological and mechanical challenge models to study inflammation. Using these approaches, we can measure the effects of both systemic and topical drugs against allergy and/or inflammation in healthy volunteers.