To study the delivery of 15 mg beclomethasone 17,21-dipropionate (BDP) to the distal part of the small bowel for three oral sustained-release formulations (I-III) and a reference capsule in volunteer ileostomists, and to compare these findings with the in vitro dissolution profiles.
The gastrointestinal passage and release of beclomethasone dipropionate from oral delivery systems in ileostomy volunteers.
CHDR
Burggraaf J, van Haarst AD, Fockens P, Schoemaker HC, Krauwinkel WJ, Cohen AF