The objective of this investigation was to assess the performance of an allometric model as the basis for interpolating drug exposure in the context of pharmacokinetic bridging across paediatric subpopulations.
Scaling of pharmacokinetics across paediatric populations: the lack of interpolative power of allometric models.
CHDR
Cella M, Knibbe C, de Wildt SN, Van Gerven J, Danhof M, Della Pasqua O
