The objective of this study was to investigate whether the pharmacokinetics of orally administered levofloxacin show 24 h variation. Levofloxacin was used as a model compound for solubility and permeability independent absorption and passive renal elimination.
Identifying 24 h variation in the pharmacokinetics of levofloxacin: a population pharmacokinetic approach.
CHDR
Kervezee L, Stevens J, Birkhoff W, Kamerling IM, de Boer T, Dröge M, Meijer JH, Burggraaf J
