Carcinoembryonic antigen is overexpressed in colorectal cancer (CRC), making it an optimal target for fluorescence imaging. A phase I/II study was designed to determine the optimal imaging dose of SGM-101 for intraoperative fluorescence imaging of primary and recurrent CRC.
Dose-Finding Study of a CEA-Targeting Agent, SGM-101, for Intraoperative Fluorescence Imaging of Colorectal Cancer.
CHDR
de Valk KS, Deken MM, Schaap DP, Meijer RP, Boogerd LS, Hoogstins CE, van der Valk MJ, Kamerling IM, Bhairosingh SS, Framery B, Hilling DE, Peeters KC, Holman FA, Kusters M, Rutten HJ, Cailler F, Burggraaf J, Vahrmeijer AL
